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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a9c62ce64ad3ea0b687c9f6f72df887e12d5bccd608f2b5216b735bd3e33946' 
  AND token = 'm9F4Ho0WCrGTZKVmAZKAbMz7wv/fLy6W2MNGXbkSk9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}