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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292cc87429d1896b7a0c1499ea465e23f5ed73ae1ffdaa63f6ded04aecc99a45' 
  AND token = 'nKtjmeCo0o/iTJLLdC6MspvPP+HFi3JW+IjonYySnPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}