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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cfe7af7b616960f94b311c9257c9c72f1e31cb0bbe07ef8a026baf822ae2398' 
  AND token = '9ezhj9hX+VSztQDdmn0bDdtnWF1dN56KsXNgFU2W+Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}