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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6015f49b99b4d945e2e3aecfd1bbed93ce33d0a724b40f344e7418911d9f9a04' 
  AND token = 'oPJtXHn6XfSzm6OEkPH4WZ4Pdj6+Q51o7qq89B2FlZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}