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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790f02251772e66108db13e3f0535a9436868aa7f1a30732a35019866caff23f' 
  AND token = 'gIMMPDRECqWH5qJRPm0OObBYlq6MYlpSDjfKJdU/B9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}