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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d64366c25b6d0370615fb284b5049c0c4146f9933bb559aec4f48e863bf2f52' 
  AND token = 'ZU+UnLT2TFuaL5Ga5j3f4SgaApsxUOtDuIlaXPy6oqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}