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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06148b225ad7d06237def60e2e2ddc1ee34e2ff7c88f3d7c302767795e0aae54' 
  AND token = 'HcvTcEw3rkn0IaalC8/BOG1yfPOTpI0MQD44a9ge2Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}