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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '329ad2c7f8c2830acd09a5127ead9fd1b4014ee8e43b006ca75c7a8245618c1b' 
  AND token = '+FTeNXHelnuZalyHriDl2NPxcKGg+Nm521e0d60FjBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}