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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0da34437154d6ab9a3b1e13f35d5fd649287b644a93251a663bfec795df0532' 
  AND token = 'gjebgXVMrltwRI4zn9AFY9aB0BP/XScWl7WarQSk4a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}