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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81487c9e8c2cd2fdf23dc349ccb40b17b16e8c5205a88f9420c4290cf149f862' 
  AND token = 'MuUbywzfUCcn2UQrjPhtWz8qtSuQtWtNJ97V7/jYpdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}