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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adbe716f03dce21ef4c83c0e2659053fdabbc255da033bd6445adfbf0ce7364c' 
  AND token = 'OwWE5Ey0VfGsm1yDLW3aoFAS9tuCEFcb2tjAV641qGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}