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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b027d8b1eb58f45163fbdeea45b1a160537222d3483a677125e6f56345dbd30' 
  AND token = 'cBNU+BaAYAroNuETM5oD4W9E6Bk2eQHStrpjLnG46XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}