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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b424ceb080279ddbcb47e74390f440b81ac64c95ae26800725b0e3a6b91a1b65' 
  AND token = 'yywHIk+dp3T+4n2uu+ZZn5X7mtALTmXzCrN0Ck+4A/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}