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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5abbb979c3bdfa21aa54320d1657ed53e18c549a1a7836d5643be285a56d6c7' 
  AND token = '7iAK8Z38mdqUGvS0UDOr9QrLFDhhTX/dQjFdxpaUNrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}