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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3341ebf55b2e4e6844b7dea1addc51439dbc12e865149b71c342810c6b9f5fd0' 
  AND token = 'XPJOHYtKmYKmXdJfvmDQI3KCy4HuMOgU1/EO1vYMMPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}