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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4f9f37fa98c10ad8186fbad39c7d792e2e4f032bed468e036ae71f3b8014c2' 
  AND token = 'GEsisJb+nSt1b44KwYgGopxPAfL0BWGbjLQEoGj54IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}