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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf528cd15b7848941aa9997e6ce115f5cf07598485e53443a2127370287fa195' 
  AND token = 'zj6svvrgS298+ffNTaDwOv+79Xa3hIc6J7xbZ1G3qmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}