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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c08643cbbf80dcfd8a58366a548d1a99a61a506a64f8818a7a17c9620de7f2e5' 
  AND token = 'SmMnpY58LGoF8oTVY7+l0+81wm8JSdCm3m0ftJNIjwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}