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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b81492872a6f7f62e0c14615b9d6c7ad828abe9aa8d21ca417015a6f0c0dbf' 
  AND token = 'zDiFk2J05zTmYirFLJBR6J3rVR1jaG2ZuoFvVcCaFi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}