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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd2550e9272002d3ef47cea93f5d873c6a2c6ac5aa0d063bdd742f0d6a4e4cc' 
  AND token = 'X8+m8R4ryLuZuAPdt47/mBlBBS96xR3iOm1zS1aFPQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}