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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23baf580c5a8bc41d1d19ac0dda4fcfb7009e2d73945108365ae4c02433c2c6b' 
  AND token = 'XaR1g2fzFZhT6SneAJCfw0v3akk2srK7hMFdgFi6nRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}