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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49b122301900d838381f5d3558fe6a2a78f79c33de98787c5ed7816b3bb655a' 
  AND token = 'x57dszBF7LoJTwTOj1a45QCh1C7nawaACbbPn8oLitc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}