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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36c9f579033176a36f13ff41a983fff4f36aba6dbb0281c39f15737a7616d52' 
  AND token = 'V2sLHDG22qdcoOXvRlJrRGuFvkV8kCH7C86SFvaKOZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}