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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49cba8b316df15501e9f16c9a7406fa7a6049df666a8fa70709165af3f49f94' 
  AND token = '1Fw4sogJB6HNSBvvXRsEaWx0psFbnehVYEfXIpaU7fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}