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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01491da7b26704f86e0dcb11574dcfcb727366671b07121bc3e641c0fff2614b' 
  AND token = '3Xof8m6jeYDuo2jFp5ciHIELXyDfKWo+bZleJe54SAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}