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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95e674b8257dc2009f68f50bd8e330d752069f578dc64baf6bb70c73edc0389' 
  AND token = '3DCutRJV9VGSuIp558DrKHEU+NelsWZoszO9wxxyM/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}