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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0251259c5c89df432351b85f0c8ebbba2d6e3e4201839e2233df03f2cc85ce53' 
  AND token = '7SXOTIDz2gfvW1WLZV0vBw6f1A1dDLfpLSmGXC9rPvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}