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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7975d1e1d963d2ba9df42947ca9afc4dc8fd4a5a95b88e69ceaa780291cece34' 
  AND token = 'B9MKv4UWfNLbOV+3Or8xu9LEzrBEcL2eGXKnEbRycmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}