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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff85c554db20226c319b6374e0bc4194999072943ce32acde4921c7d81c02f4' 
  AND token = 'WBAcmg7st6S49LpH6N9ztG4ff+1+nv/4LuEmS7iIhdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}