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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e315a55ca9987c676778139d63962316b9877e816c3dd644b6f366d2006cddf2' 
  AND token = 'BxfF/BzcVSs+406NtHOQnN1Rtv9Da956xGttG3QUI10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}