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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c641330f8f917e1155c566aa5cc5f8eccf693cc3e550849454c97443e474244' 
  AND token = '+uY//tzYHForCoPa57oKw6HcbYdALkCNGBMT582SK94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}