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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578b38f18363cd5033750051a75253ab3f95950754332fc40355679991a25fae' 
  AND token = 'xTQY+k9quy5Xgyqy8jABvTCv4gdLzsjpAT8iuZUP8+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}