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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b043e21c8e85efa404a98927c1b7c32ccd66cedf5f3bc8c1ff54874115517abe' 
  AND token = '5gJlfXCcVX7+SWbL0e3FiXBjGUGOE5QPlVJmuCkKu5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}