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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ffbab9f919751ada3475b0c70174ad5d2fbcc7dae224f05dd2e8b3273a824b3' 
  AND token = 'qRVlOug2lY5I0bCz6CuzMwf6y7bUjJzfcf++qWOFu2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}