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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8753829630a49a29d789f8f26baa4e75114e092ac7f85e24eddb3dac3b78ec5b' 
  AND token = '070XOrQMXHqb5+uc8dC//UFFLFr/sbX1OBVuDWZ4hEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}