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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5451bba79f8a801cbd95ef7c741bde6ceab8770f5b6fb282a0392398e8be60d9' 
  AND token = '5TkI0D7kZuELlT9tJLyDcB7MGDpLE5lfbs8Qo1Xt3V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}