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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df5d2606ae13d1dfb95c61532a9714cae64fe04384005b13c92c2f7b9ae3f43f' 
  AND token = 'LZwxU1RLaNumG3rSeM6cj5YaUw4kWyV7ne9thDdgpe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}