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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ff0c19df3aa3e8549fc32942b6879ef6d9c22c80dc4cfb51e64b4518482476' 
  AND token = 'OD/17VZ7KN1h92YBMP46nHUfnzt0DTlMpYVcetHSv5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}