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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a545a56bc16f64f52bf5bbc12426e69029d913024908d0efdece292cb4a03a48' 
  AND token = 'HFE8ZhmuAXazQmom8roqC/PqPhieO1SXmDZJogKP3ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}