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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec364bf47e788034fd19fd8d7818d1fa549a166da3589a0bb7805db614c11854' 
  AND token = 'IBt1XiR8OrWurUabfz7JGWsJ1sXlf3jWF03+6KEtwxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}