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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327fcd140f74086a537afce8b7216a810843256691d6ce61f408f8e0f635ef37' 
  AND token = 'NnXVIMmtbnsFbja89Z+rAQtoLWR2CHeGCsKPwJaor10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}