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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6265d097ed56f80356f145025dbf0529649f02ffbd6fe8de56c39b1cdb8fbb69' 
  AND token = 'PkULPz0n8k9Sy9jSMbXSr65SE4aPEfn0rWdj60MMOIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}