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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b8177b073e1c82d41e36e4262a9a83148825918569b43428caee5e2634d49c0' 
  AND token = '+/W0XiBhXB4NHT8RO8FEe8YFyI9iyJJc2aAoUKSiF+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}