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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9b01d3b62a9c9ed5f0e9774c3cc864aeb5a55dbafcd6076c653c813419290f0' 
  AND token = '65dm+5uTnv4iUF+RiJaK8xqL1NJoaRAwso4KXwYcY4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}