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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16046497640d75272d248877cb783bcff3911b3899f4967730b4db3cf7520da8' 
  AND token = 'eMnxxeh/hx1wetk8wHtY/J5y9n7Eh1YjpLwXiJh8DEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}