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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f67fb525af99637b5e7baffedb906a3fbb022217c4c4c30174261b0990d22b01' 
  AND token = 'AmnPRtf5kvWb/ZBpzpd31VqYr8WnKZw1XeLmsFte9A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}