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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efe9cced207ffa0d47c43e597a80c958e946b4c124415583be0dfb704b0b2ee' 
  AND token = 'gHzcE44fcdhY7rPtbrJOQFeI1ly9MOVaZaSy7hAwqzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}