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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110f1088204e593769e7720f9ea8fd2964fa155d0cfffebbf51710be0bff1161' 
  AND token = '1AoAWMW1aFJS/CH/oPHLm0M5p/7GynMmq5RL83gcoJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}