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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6de3f403c21301fe11f8d704c290075cd451f06b1941be1d5c9e70962d76c28' 
  AND token = 'lMgcnTdeugl7DfwZpPNPp/nDbNvmqQ9zabAdOmK0BwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}