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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8ba87c7f08c1eca4a3f54e5e093655466ad0ab90b190859c4d34df0a951b24' 
  AND token = 'ItOFbsCUyJNmUxGyzRiB9yO6kzFZ0p1Pdb96VG8I+Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}